Stage

Biochemistry

Location

Property

T1W

T2W

Mnemonic

Hyperacute (hrs)
oxy-Hb
intracellular
Dimagnetic
isointense
bright
IB
Acute (1-2 days)
deoxy-Hb
intracellular
paramagnetic
isointense
dark
ID
Early subacute (2-7 days)
Met-Hb
intracellular
paramagnetic
bright
dark
BD
Late subacute (1-4 wks)
Met-Hb
extracellular
paramagnetic
bright
bright
BaBy
Chronic
Hemosiderin
extracellular
ferromagnetic
dark
dark rim
DooDoo








Appearance of intracranial hemorrhage on MR depends on the age of the hematoma and the sequence (Tl or T2 weighted).

As hematoma ages, hemoglobin passes through different forms (oxyhemoglobin à deoxyhemoglobin à methemoglobin) prior to red cell lysis and breakdown into hemosiderin.

Mnemonic
Stage
T1
T2
It Be
Hyperacute
isointense (I)
hyperintense (B)
IdDy
Acute
iso to hypointense (I)
hypointense (D)
BiDdy
Early Subacute
hyperintense (B)
hypointense (D)
BaBy
Late Subacute
hyperintense (B)
hyperintense (B)
Doo Doo
Chronic
hypointense (D)
hypointense (D)

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